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<journal-id journal-id-type="publisher">london-journal-of-medical-and-health-research</journal-id>
<journal-title-group>
<journal-title>London Journal of Medical and Health Research</journal-title>
</journal-title-group>
<issn publication-format="print">2515-5784</issn>
<issn publication-format="electronic">2515-5792</issn>
<publisher><publisher-name>JournalsPress</publisher-name></publisher>
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<article-id pub-id-type="doi">10.34257/LJMHR226766UK</article-id>
<article-id pub-id-type="publisher-id">226766</article-id>
<title-group>
<article-title>Diabetic Foot : A Multidisciplinary Approach up to Limb Preservation</article-title>
<subtitle>Multidisciplinary Approach to Diabetic Foot Care</subtitle>
</title-group>
<contrib-group>
<contrib contrib-type="author"><name><surname>Amonkar</surname><given-names>Amol</given-names></name><xref ref-type="aff" rid="aff1" />
</contrib>
<contrib contrib-type="author"><name><surname>Gonsalves</surname><given-names>Dr. Wilroy</given-names></name><xref ref-type="aff" rid="aff2" />
</contrib>
<contrib contrib-type="author"><name><surname>Souza</surname><given-names>Dr. Kiara De</given-names></name><xref ref-type="aff" rid="aff3" />
</contrib>
<contrib contrib-type="author"><name><surname>Fernandes</surname><given-names>Dr. Mayble</given-names></name><xref ref-type="aff" rid="aff4" />
</contrib>
<contrib contrib-type="author"><name><surname>Filinto-Sequeria</surname><given-names>Dr. Ella-Marie</given-names></name><xref ref-type="aff" rid="aff5" />
</contrib>
<contrib contrib-type="author"><name><surname>Bhembre</surname><given-names>Dr. Shalaka Prabhu</given-names></name><xref ref-type="aff" rid="aff6" />
</contrib>
<contrib contrib-type="author"><name><surname>Cardoso</surname><given-names>Dr. Swizel Ann</given-names></name><xref ref-type="aff" rid="aff7" />
</contrib>
<contrib contrib-type="author"><name><surname>Gouveia</surname><given-names>Dr. Shanice Marisa</given-names></name><xref ref-type="aff" rid="aff8" />
</contrib>
<contrib contrib-type="author"><name><surname>Coutinho</surname><given-names>Dr. Abigail</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Kunde</surname><given-names>Manasvi Mandar Shenvi</given-names></name></contrib>
<contrib contrib-type="author"><name><surname>Kandpal</surname><given-names>Manvendra Dutt</given-names></name></contrib>
</contrib-group>
<aff id="aff1">INDIA, Goa Medical College</aff>
<aff id="aff2">UNITED KINGDOM, Southampton General Hospital</aff>
<aff id="aff3">UNITED KINGDOM, Community CAMHS, North East London Foundation Trust</aff>
<aff id="aff4">Good Hope Hospital, University Hospitals Birmingham NHS Foundation Trust</aff>
<aff id="aff5">UNITED KINGDOM, Kettering General Hospital</aff>
<aff id="aff6">Doncaster Royal Infirmary, Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust</aff>
<aff id="aff7">Wexham Park Hospital, Frimley NHS Foundation Trust</aff>
<aff id="aff8">UNITED KINGDOM, King&#039;s College Hospital</aff>
<pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-06-17">
<day>17</day>
<month>06</month>
<year>2026</year>
</pub-date>
<volume>26</volume>
<issue>4</issue>
<fpage>1</fpage>
<lpage>11</lpage>
<abstract><p>Diabetic foot is a major chronic complication of diabetes mellitus and represents a leading cause of hospitalisation, infection and non- traumatic lower limb amputation worldwide. The pathogenesis is multifactorial primarily involving peripheral neuropathy, peripheral arterial disease, impaired immunity and poor glycemic control which together predispose patients to ulceration and delayed wound healing. This review of literature aims to summarise current evidence regarding epidemiology, risk factors clinical evaluation and treatment strategies for diabetic foot disease. The literature consistently demonstrates that early identification of at-risk patients through routine screening and structured risk stratification significantly reduces ulcer occurrence. Management of established diabetic foot ulcers requires a multi-disciplinary approach combining glycemic control, infection management using culture guided antimicrobial therapy, regular wound debridement, appropriate wound dressings and appropriate offloading techniques.In patients with associated ischaemia, timely vascular assessment followed by endovascular or surgical revascularisation is critical for limb salvage. Advanced adjunctive therapies including negative pressure wound therapy, bioengineered skin substitutes and growth factor- based treatments have shown beneficial outcomes in selected cases. Overall, comprehensive preventive programs and standardised multidisciplinary treatment protocols remain essential for reducing amputation rates and improving functional outcomes in patients with diabetic foot disease.</p></abstract>
<kwd-group kwd-group-type="author-generated">
<kwd>diabetic foot</kwd>
<kwd>ulcer</kwd>
<kwd>management</kwd>
<kwd>treatment</kwd>
<kwd>peripheral vascular disease.</kwd>
</kwd-group>
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<p>Diabetic foot is a major chronic complication of diabetes mellitus and represents a leading cause of hospitalisation, infection and non- traumatic lower limb amputation worldwide. The pathogenesis is multifactorial primarily involving peripheral neuropathy, peripheral arterial disease, impaired immunity and poor glycemic control which together predispose patients to ulceration and delayed wound healing. This review of literature aims to summarise current evidence regarding epidemiology, risk factors clinical evaluation and treatment strategies for diabetic foot disease. The literature consistently demonstrates that early identification of at-risk patients through routine screening and structured risk stratification significantly reduces ulcer occurrence. Management of established diabetic foot ulcers requires a multi-disciplinary approach combining glycemic control, infection management using culture guided antimicrobial therapy, regular wound debridement, appropriate wound dressings and appropriate offloading techniques.In patients with associated ischaemia, timely vascular assessment followed by endovascular or surgical revascularisation is critical for limb salvage. Advanced adjunctive therapies including negative pressure wound therapy, bioengineered skin substitutes and growth factor- based treatments have shown beneficial outcomes in selected cases. Overall, comprehensive preventive programs and standardised multidisciplinary treatment protocols remain essential for reducing amputation rates and improving functional outcomes in patients with diabetic foot disease.</p>
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