Vaginal Infection is the most common problem which almost most girls suffer. It is neglected but it has a serious effect if it is not treated. It is diagnosed if the color of the vaginal discharge changes, has a strong fishy odor, irritation, and burning sensation. The normal microflora of the vagina, that as the first line of defense in preventing the infection from pathogenic fungi, bacteria or protozoa which can cause vaginal infection. Several treatment strategies have been adapted for vaginal infections. Vaginitis trigger UTI (Urinary Tract Infection) in most of the girls. This review, is focused on vaginal infections caused by different types of microorganisms, symptoms and their treatment method.