A simple, precise, accurate, and economical UV visible spectrophotometric method has been developed for estimation of Perindopril erbumine & Indapamide drug by AUC method. Quantitative determination of the drug was performed at wavelength range 208-214 nm and 239-244 nm for Perindopril erbumine & Indapamide respectively. The linearity was established over the concentration range of 10-50 µg/ml for Perindopril erbumine and 1-5 µg/ml for Indapamide with correlation coefficient value of 0.999 for both the drugs. Precision studies showed that % relative standard deviation was within range of acceptable limits. The recovery study was found to be within range of 99-101%. The proposed method has been validated as per ICH guidelines.
A simple, precise, accurate, and economical UV visible spectrophotometric method has been developed for estimation of Perindopril erbumine & Indapamide drug by AUC method. Quantitative determination of the drug was performed at wavelength range 208-214 nm and 239-244 nm for Perindopril erbumine & Indapamide respectively. The linearity was established over the concentration range of 10-50 µg/ml for Perindopril erbumine and 1-5 µg/ml for Indapamide with correlation coefficient value of 0.999 for both the drugs. Precision studies showed that % relative standard deviation was within range of acceptable limits. The recovery study was found to be within range of 99-101%. The proposed method has been validated as per ICH guidelines.