Some Thoughts Regarding the Narrative of the Current Nosological Schema and their Ramifications for Major Mental Disorders with a Focus on Schizophrenia

The current nosological schema for major mental disorders does not capture all the clinical phenomena, especially those being observed longitudinally (i.e., six decades of clinical observations of over eight thousand patients suffering with emotional problems of which three thousands of them suffer from major mental disorders, spanning two to three generations by the author). The objective of this article is to point out that these overlooked in their collective significance phenomena—even though they are noted by the clini- cians, are not part of the categorical guidelines of the current schema. They have ramifications for better conceptualizing the road-guide in our future research for these baffling, major mental disorders, including schizophrenia, bipolar affective disorder, obsessive-compulsive disorder (OCD), anxiety, and attention deficit hyperactivity disorder (ADHD), which are sharing a common, neuro-developmental origin.

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The authors declare no conflict of interest.

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The datasets used in this study are openly available at [repository link] and the source code is available on GitHub at [GitHub link].

This work did not receive any external funding.