An Insight into Pharmacological Profile of Hydroxy Cinnamic Acid, an Active Constituent of Ferulic Acid Reviewing

Ferulic acid, a hydroxyl cinnamic acid derivative, belonging to natural phenolic compound category is known for its anti-inflammatory actions. As Inflammatory diseases are one of the major causes of raised chronic diseases in human body that can be cured by the help of ferulic acid. The functional organs of body that are more prone to the pathogens due to the invasive ingestions and changing lifestyle can also be treated by the help of ferulic acid. This biological native substance is active in protective measures of various acquired diseases. The anti-inflammatory effect of ferulic acid is due to the chemical structure similarity with curcumin which inhibits reactive oxygen species (ROS), inflammatory biomarkers including cytokines, inflammosomes, TNF-α and C-reactive protein (CRP) etc. Also, the presence hydroxyl cinnamic acid group within the ring helps in suppression of free radicals during excessive free radicals formation. Its anti-inflammatory and activity against oxidative stress makes it helpful and potential compound for the treatment in various neuro-inflammatory diseases such as Parkinson’s diseases, Alzheimer’s diseases, etc. in recent studies, it has also found the anti-inflammatory properties of ferulic acid can be utilized in Cancer studies, Immune disorders and aging.

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The authors declare no conflict of interest.

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The datasets used in this study are openly available at [repository link] and the source code is available on GitHub at [GitHub link].

This work did not receive any external funding.