Abstract
Dermatophytes are filamentous fungi that affect both human and animal skin, hair, and nails. There is a public health issue with it. In order to ascertain the effects of the methanolic extracts of Buccholzia coriacea on the isolates and the sensitivity level of the isolates to common antifungal drugs, this study was developed to explore the prevalence of Dermatophytes from clinical cases in horses. Samples were initially cultivated on Sabouraud dextrose agar, and then on Potato dextrose agar (secondary culture). Twelve (12%) of the sixty (60) clinical samples that were obtained were positive for Dermatophytes. T. rubrum (1), T. verrucosum (3), T. equinum (3), M. audounii (2), and M. gypseum (3) were the species recognized. At concentrations between 125 and 250 mg/ml, the methanolic extract of Buccholzia coriacea demonstrated antifungal effects on every isolate with values for the minimum inhibitory concentration (MIC)
and minimum fungicidal concentration (MFC). The isolates' susceptibility to six popular antifungal medications was assessed. The isolates were well inhibited by Ketoconazole and terbinafine, but none of them were susceptible to amphotericin B. This study was able to show that Buccholzia coriacea's methanolic extract has antifungal properties. Additionally, two Dermatophytes species (Trichophyton and Microsporum) from Katsina state, Nigeria, were able to be isolated for this study.
Conflict of Interest
The authors declare no conflict of interest.
Ethical Approval
Not applicable
Data Availability
The datasets used in this study are openly available at [repository link] and the source code is available on GitHub at [GitHub link].
Funding
This work did not receive any external funding.
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