Abstract
Endorphins are endogenous morphine, produced in pituitary gland response to stress. There are three types of endorphins beta endorphins, enkephalins, and dynorphins binds to mu, kappa, and delta receptors situated on nervous system and immune cells. Beta-endorphins are abundant endorphins has an analgesic activity both in peripheral nervous system and central nervous system. This article highlights about the holistic approach of beta-endorphins in palliative management of cancer pain
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