Oxygen Therapy and Ventilation for the Management of Patients with Covid-19 in Intensive Care

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Abstract

Introduction Covid-19 patients who present with severe conditions, often require oxygen support. This study aimed to describe oxygen therapy and ventilation techniques and outcomes.
Methods We conducted a retrospective descriptive study at the Covid-19 center in Lomé. Patients who received oxygen therapy or mechanical ventilation in the intensive care unit (ICU), between September 1, 2020, and May 31, 2021, were included.
Results
Of 1073 patients admitted to the center, 134 patients were included in the study. The mean age was 60.53 ± 13.6 years and the sex-ratio was 1.27. One hundred and three patients
(76,87%) had at least one comorbidity, including hypertension (55.22%), diabetes (41.79%), and obesity (15.67%). Median SpO2 was 83% (IQR 74-88%). Conventional oxygen therapy was applied in 132 patients (98,51% patients), non-invasive ventilation (NIV) in 41 patients (30.60%) and invasive mechanical ventilation (IMV) in 37
(21.61%).

Under COT, 35.82 % of patients recovered and 64,18 % died. Out of NIV(41) patients, 9.8% recovered, 58.54% escalated to IMV and 31.71% died. With IMV (37 patients), 100 % died.
The mortality rate was 64.18%, caused by acute respiratory distress syndrome (60.45%), pulmonary embolism (23.80%), and multiple visceral failures (11.19%).
Conclusion COT, NIV, and IMV are the procedures of oxygen support in Covid-19 patients. The mortality rate is high, especially with IMV.

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

Not applicable

Data Availability

The datasets used in this study are openly available at [repository link] and the source code is available on GitHub at [GitHub link].

Funding

This work did not receive any external funding.

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  • Classification

    DDC Code: 697 LCC Code: TH7222

  • Version of record

    v1.0

  • Issue date

    November 2022

  • Language

    English

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