Pancreatic Fistula, Hemorrhage and Delayed Gastric Emptying: A Major Complication of Pancreaticoduodenectomy

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Research ID 9D937

Abstract

Pancreaticoduodenectomy remains a major therapy in the management of adenocarcinoma of the head of the pancreas and the biliary-digestive tract tumors. Postoperative morbidity and mortality remain high. An operative mortality  less than 5% in reference centers but can up to 25-50% in others  hospitals. These complications are diverse, namely, early hemorrhage, which has the highest postoperative mortality rate, pancreatic fistula, which remains the feared complication,  with its attendant complications, and Delayed Gastric Emptying, which remains the most frequent. The CT scan remains the gold standard for monitoring and detecting.No precise etiology could be found for these complications but some risk factors were found. The management of these complications depends on the degree of damage and the hemodynamic state of the patient.  The International study group of pancreatic surgery (ISGPS) proposed a classification to harmonize the diagnosis, the degree of these complications, and the appropriate management. 

Conflict of Interest

The authors declare no conflict of interest.

Ethical Approval

Not applicable

Data Availability

The datasets used in this study are openly available at [repository link] and the source code is available on GitHub at [GitHub link].

Funding

This work did not receive any external funding.

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  • Classification

    NLMC CODE: WG 590

  • Version of record

    v1.0

  • Issue date

    04 October 2021

  • Language

    English

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