Development and Validation of Uv Spectrophotometric Estimation of Perindopril Erbumine and Indapamide in Bulk and Tablet Dosage by Using Area Under Curve Method

Abstract

A simple, precise, accurate, and economical UV visible spectrophotometric method has been developed for estimation of Perindopril erbumine & Indapamide drug by AUC method. Quantitative determination of the drug was performed at wavelength range 208-214 nm and 239-244 nm for Perindopril erbumine & Indapamide respectively. The linearity was established over the concentration range of 10-50 µg/ml for Perindopril erbumine and 1-5 µg/ml for Indapamide with correlation coefficient value of 0.999 for both the drugs. Precision studies showed that % relative standard deviation was within range of acceptable limits. The recovery study was found to be within range of 99-101%. The proposed method has been validated as per ICH guidelines.

Citations

Seemarani Pawar. 2023. "Development and Validation of Uv Spectrophotometric Estimation of Perindopril Erbumine and Indapamide in Bulk and Tablet Dosage by Using Area Under Curve Method". London Journal of Medical and Health Research LJMHR Volume 23 (LJMHR Volume 23 Issue 1): NA.

Related Research

  • Classification

    DDC Code: 610.3 LCC Code: R121

  • Version of record

    v1.0

  • Issue date

    NA

  • Language

    English

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