IntelliPaper
Abstract
Chikungunya virus (CHIKV) infection has been linked to severe neurological outcomes, notably Guillain-Barré Syndrome (GBS). This systematic review highlights clinical and mechanistic evidence associating CHIKV with autoimmune polyradiculoneuropathies. Findings reveal the virus’s neurotropism and support its role as a triggering factor for GBS. Despite methodological heterogeneity among studies, the evidence underscores important implications for diagnosis, clinical surveillance, and patient management. Deeper understanding of this relationship is essential to improve preventive and therapeutic health strategies.
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Conflict of Interest
The authors declare no conflict of interest.
Ethical Approval
Not applicable
Data Availability
The datasets used in this study are openly available at [repository link] and the source code is available on GitHub at [GitHub link].
Funding
This work did not receive any external funding.
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